-Disgustingly servile or obsequious in behaviour.
-Obedient or attentive to an excessive or servile degree.
Origin unknown-ish, but the original documentation of this word comes from a book with the Brobdingnagian title “A Glossary of Yorkshire Words and Phrases, Collected in Whitby and the Neighbourhood, with Examples of Their Colloquial Use, and Allusions to Local Customs and Traditions.” by Francis Kildale Robinson, 1809-1882 - wherein it gives this definition:-puzzom 'poison', puzzomful 'poisonous', and puzzomous 'poisonous'.
So one may ask where do we get “servile” or “obsequious” from “poison”? As it turns out, a now archaic definition for obsequious is “dutiful in regard to the dead and in the proper and appropriate performance of obsequies (funeral rites).”
Used in a sentence:
"Gwenda told that mammothrept little carker, Dermot, to stop being so blatantly puzzomous.”